diff --git a/tests/pipeline/test_filter.py b/tests/pipeline/test_filter.py
index f1d33d7c..fe4d5435 100644
--- a/tests/pipeline/test_filter.py
+++ b/tests/pipeline/test_filter.py
@@ -11,6 +11,8 @@ from numpy import (
     eye,
     float64,
     full_like,
+    inf,
+    isfinite,
     nan,
     nanpercentile,
     ones,
@@ -333,3 +335,37 @@ class FilterTestCase(BasePipelineTestCase):
             dtype=bool,
         )
         check_arrays(results['with'], expected_with)
+
+    def test_isnan(self):
+        data = self.randn_data(seed=10)
+        diag = eye(*data.shape, dtype=bool)
+        data[diag] = nan
+
+        results = self.run_graph(
+            TermGraph({'isnan': self.f.isnan()}),
+            initial_workspace={self.f: data},
+        )
+        check_arrays(results['isnan'], diag)
+
+    def test_notnan(self):
+        data = self.randn_data(seed=10)
+        diag = eye(*data.shape, dtype=bool)
+        data[diag] = nan
+
+        results = self.run_graph(
+            TermGraph({'notnan': self.f.notnan()}),
+            initial_workspace={self.f: data},
+        )
+        check_arrays(results['notnan'], ~diag)
+
+    def test_isfinite(self):
+        data = self.randn_data(seed=10)
+        data[:, 0] = nan
+        data[:, 2] = inf
+        data[:, 4] = -inf
+
+        results = self.run_graph(
+            TermGraph({'isfinite': self.f.isfinite()}),
+            initial_workspace={self.f: data},
+        )
+        check_arrays(results['isfinite'], isfinite(data))
diff --git a/zipline/pipeline/expression.py b/zipline/pipeline/expression.py
index b4d100b0..1b13b22c 100644
--- a/zipline/pipeline/expression.py
+++ b/zipline/pipeline/expression.py
@@ -10,6 +10,7 @@ from numexpr.necompiler import getExprNames
 from numpy import (
     empty,
     find_common_type,
+    inf,
 )
 
 from zipline.pipeline.term import Term, NotSpecified, CompositeTerm
@@ -212,6 +213,8 @@ class NumericalExpression(CompositeTerm):
         variable_names, _unused = getExprNames(self._expr, {})
         expr_indices = []
         for name in variable_names:
+            if name == 'inf':
+                continue
             match = _VARIABLE_NAME_RE.match(name)
             if not match:
                 raise ValueError("%r is not a valid variable name" % name)
@@ -239,7 +242,7 @@ class NumericalExpression(CompositeTerm):
                 "x_%d" % idx: array
                 for idx, array in enumerate(arrays)
             },
-            global_dict={},
+            global_dict={'inf': inf},
             out=out,
         )
         return out
diff --git a/zipline/pipeline/factors/factor.py b/zipline/pipeline/factors/factor.py
index 78cb9b2a..0fadb497 100644
--- a/zipline/pipeline/factors/factor.py
+++ b/zipline/pipeline/factors/factor.py
@@ -8,6 +8,7 @@ from numpy import (
     apply_along_axis,
     float64,
     nan,
+    inf,
 )
 from scipy.stats import rankdata
 
@@ -343,6 +344,29 @@ class Factor(CompositeTerm):
             mask=mask,
         )
 
+    def isnan(self):
+        """
+        A Filter producing True for all values where this Factor is NaN.
+        """
+        return self != self
+
+    def notnan(self):
+        """
+        A Filter producing True for values where this Factor is not NaN.
+
+        Returns
+        -------
+        nanfilter : zipline.pipeline.filters.Filter
+        """
+        return ~self.isnan()
+
+    def isfinite(self):
+        """
+        A Filter producing True for values where this Factor is anything but
+        NaN, inf, or -inf.
+        """
+        return (-inf < self) & (self < inf)
+
 
 class NumExprFactor(NumericalExpression, Factor):
     """
diff --git a/zipline/pipeline/filters/filter.py b/zipline/pipeline/filters/filter.py
index 9869e910..61d214d3 100644
--- a/zipline/pipeline/filters/filter.py
+++ b/zipline/pipeline/filters/filter.py
@@ -83,6 +83,30 @@ def binary_operator(op):
     return binary_operator
 
 
+def unary_operator(op):
+    """
+    Factory function for making unary operator methods for Filters.
+    """
+    valid_ops = {'~'}
+    if op not in valid_ops:
+        raise ValueError("Invalid unary operator %s." % op)
+
+    def unary_operator(self):
+        # This can't be hoisted up a scope because the types returned by
+        # unary_op_return_type aren't defined when the top-level function is
+        # invoked.
+        if isinstance(self, NumericalExpression):
+            return NumExprFilter(
+                "{op}({expr})".format(op=op, expr=self._expr),
+                self.inputs,
+            )
+        else:
+            return NumExprFilter("{op}x_0".format(op=op), (self,))
+
+    unary_operator.__doc__ = "Unary Operator: '%s'" % op
+    return unary_operator
+
+
 class Filter(CompositeTerm):
     """
     Pipeline API expression producing boolean-valued outputs.
@@ -96,6 +120,7 @@ class Filter(CompositeTerm):
             for op in FILTER_BINOPS
         }
     )
+    __invert__ = unary_operator('~')
 
 
 class NumExprFilter(NumericalExpression, Filter):