diff --git a/skimage/io/tests/test_pil.py b/skimage/io/tests/test_pil.py
index f54fa9e3..68a21cf0 100644
--- a/skimage/io/tests/test_pil.py
+++ b/skimage/io/tests/test_pil.py
@@ -65,7 +65,7 @@ def test_bilevel():
 def test_imread_uint16():
     expected = np.load(os.path.join(data_dir, 'chessboard_GRAY_U8.npy'))
     img = imread(os.path.join(data_dir, 'chessboard_GRAY_U16.tif'))
-    assert img.dtype == np.uint16
+    assert np.issubdtype(img.dtype, np.uint16)
     assert_array_almost_equal(img, expected)
 
 @skipif(not PIL_available)
@@ -97,3 +97,6 @@ class TestSave:
                 else:
                     x = (x * 255).astype(dtype)
                     yield self.roundtrip, dtype, x
+
+if __name__ == "__main__":
+    run_module_suite()